Our laboratory aims to understand how cells can be manipulated and engineered to facilitate targeted delivery of therapeutics and regulate intercellular interactions, in order to improve and innovate therapies for cancers, injured tissues, autoimmune disorders, and other diseases. In one path towards this goal, we utilize chemistry, chemical biology, and synthetic biology tools to modify or engineer cells for subsequent tracking and targeted modulation in vivo. In another path, we develop biomaterials that can home and manipulate immune cells in vivo, and apply them to the development of cancer vaccines, cell therapies, and medical devices. New molecules, polymers, and biomaterials that can serve as diagnostics, therapeutics, and medical supplies/devices are also of our interest.